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    SOLVED ARDS筆記提問

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    • R
      rain776779 last edited by MegaNote

      ARDS 筆記連結

      0_1485439116062_image.png

      第一點sepsis:酗酒者的風險更高?
      對於酗酒者有疑問沒有看到有文獻這樣指出
      是因為酗酒者的意識混亂
      較容易aspiration pneumonia?
      還是說immune suppression?
      這部分不太清楚><

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        omm last edited by

        咦為什麼幹細胞移植要搭配高劑量放化療?😊

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          LWF last edited by

          先高劑量化放→移植?

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            TinyNotes @rain776779 last edited by TinyNotes

            @rain776779
            相關文獻:

            • Chronic alcohol abuse, acute respiratory distress syndrome, and multiple organ dysfunction.
              連結:https://www.ncbi.nlm.nih.gov/pubmed/12682442

            • Risk factors for the development of acute lung injury in patients with septic shock: an observational cohort study.
              連結:https://www.ncbi.nlm.nih.gov/pubmed/18434908

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              TinyNotes @rain776779 last edited by

              @rain776779
              可能的解釋:

              • 減少上皮液體中的glutathione濃度,進而讓肺臟更容易受到氧化壓力的影響
              • 慢性酗酒可能會導致白血球不正常的附著於內皮細胞
                (細節可參考uptodate:Acute respiratory distress syndrome: Epidemiology, pathophysiology, pathology, and etiology in adults)
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                TinyNotes @omm last edited by

                @omm
                在Leukemia的患者,若要進行幹細胞移植,需要先進行高劑量的放化療,之後再輸注幹細胞進入體內,可參考下圖。
                alt text

                這些患者得到ARDS的原因則更為複雜,包括感染性因素、放化療本身的傷害、移植物的攻擊等。

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                  TinyNotes @rain776779 last edited by

                  @rain776779
                  希望這樣有解決你的問題~~ 😃

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