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為減少K+排出，所以 改排H+ 到lumen， 又NA+- H+ PUMP 排H+留Na+ 管中 H+多 HCO3- 回收變多
但是Proximal tubule 的 intracellular acidosis又會讓bicarbonate再吸收下降
想請問這樣有沒有牴觸? 詳細的作用機轉是?